Participate in Epilepsy Research
Participating in epilepsy research has the potential to not only improve your own condition but also help others by increasing our understanding of epilepsy, developing new treatments, and possibly even preventing epilepsy. In some cases, participating in clinical trials and other research studies involves certain risks, so be sure to discuss these risks and possible benefits with your doctor before enrolling in any research study. For additional information on clinical trials and other research in which you can participate, visit the Epilepsy Foundation’s Participate in Epilepsy Research page.

Research Studies and Clinical Trials currently recruiting in Michigan (note: this list is not comprehensive)

Stereotactic Laser Ablation for Temporal Lobe Epilepsy (SLATE) - This study is designed to evaluate the safety and efficacy of the Visualase MRI-guided laser ablation system for mesial temporal epilepsy (MTLE). Henry Ford Health System is currently recruiting participants. Contact: Lisa Scarpace 313-916-2360 Principal Investigator: Jason Schwalb, MD 

Prospective Randomized 12-week Controlled Study Of Visual Field Change In Subjects With Partial Seizures Receiving Pregabalin Or Placebo - Volunteers are needed to participate in a clinical research study of an investigational medication for add-on treatment of epilepsy. You may qualify for this 3-month study if: you are between the ages of 18 and 65; you have a diagnosis of epilepsy with partial seizures; and you are currently taking 1 to 3 antiepileptic drugs. For more information, please contact Dr. Maysaa Basha, Attn: Amy Spencer, Research Assistant, Department of Neurology (313-745-7836;

VALOR Study - The VALOR study is seeking volunteers to test how an investigational medicine called lacosamide works with your current anti-epileptic medication. Study participants must be 4 years or older and currently suffering from primarily generalized tonic-clonic (or "grand mal") seizures. For more information, please contact Aubrey Alexander - 517-884-8920; .

The FAiRE-LGS study is an ongoing research study to evaluate whether an investigational drug called ZX008 (Fenfluramine Hydrochloride, oral solution) can reduce the number of seizures experienced by children and adults with Lennox-Gastaut Syndrome (LGS). This study will involve 2 parts: Part 1 is a fixed-dose, weight-based, double-blind portion that is approximately 20 weeks, and it is followed by Part 2, an open-label safety extension that is approximately 54 weeks. To take part, participants must meet diagnostic criteria for LGS with no alternative diagnosis, be between 2 and 35 years of age, have uncontrolled seizures despite current medications, and be receiving stable doses of medications that are not being changed during the study. For more information, you may also visit, email, or call 1-866-ZOGENIX (1-866-964-3649, select option 1, then option 1 again).

Johns Hopkins EpiWatch App and Research Study - Johns Hopkins EpiWatch is an app for Apple Watch and a research study. EpiWatch helps you manage your epilepsy by tracking your seizures and possible triggers, medications, and side effects. EpiWatch is not a seizure detector. You should not rely on EpiWatch to get help for your seizures. In collaboration with Citizens United for Research in Epilepsy (CURE), Johns Hopkins is donating Apple Watches to eligible study participants who possess (or can obtain) iPhones and who have histories of tonic-clonic seizures, especially nocturnal tonic-clonic seizures,​ in the past several months. Possible participants can call 443-287-3042 to review eligibility and participation with a research assistant.

Human Epilepsy Project
 - a five-year, prospective, observational study whose primary goal is to identify clinical characteristics and biomarkers predictive of disease outcome, progression, and treatment response in participants with newly treated focal epilepsy; University of Michigan is a study site; for more information, contact Julie Konkle, BSN, RN, CCRP, Clinical Research Project Manager (734-936-8036).

Established Status Epilepticus Treatment Trial (ESETT) - a study to find out which of three commonly used medicines given in the emergency department for established status epilepticus is safer and more effective. This is an "exception from informed consent study." Normally, researchers get permission before a person can be included in a study. Since a seizure that will not stop on its own must be treated quickly, there will not be enough time to locate and talk to the person’s legal representative about the study, so the person will be enrolled in the study without consent. Once the representative is located or the patient wakes up, they will be asked to give their permission to continue in the study. If you would like more information about the study or would like to decline participation, please call 313-745-4350 or email

Epilepsy Self-Management Survey - Researchers from the Morehouse School of Medicine, Emory University, and the Managing Epilepsy Well Network are conducting a survey of Black or African American adults (age 18 or older) who've been told that they have epilepsy or seizure disorder. They want to learn how adults with epilepsy or seizure disorder take care of their condition. The survey takes 20 to 25 minutes to complete, and if you submit the survey, you will get a $5.00 gift card to thank you for your time. This research is based at the Morehouse School of Medicine and is sponsored by the Centers for Disease Control and Prevention Epilepsy Program. Learn more and complete the survey, or contact the research team at or 404-756-8848 if you have questions.

Clinical Trials Currently Recruiting in Michigan

Epilepsy Foundation's Clinical Trials Portal